微波反應監控
微波輔助合成正迅速成為現代合成與探索化學實驗室中的首選方法。
微波輔助合成透過大幅縮短反應時間、提高產率並獲得更純淨的產物，為化學家提升了產能與周轉時間。
將微波技術與原位反應監測作為分析工具相結合的能力，將為化學家提供優化反應條件的機會。
Enwave Optronics 開發 EZRaman 型號，以幫助最佳化微波增強合成的反應條件，例如時間和溫度。
參考文獻
- Nicholas E Leadbeater, Jason R Schmink, 2008, Use of Raman spectroscopy as a tool for in situ monitoring of microwave-promoted reactions. Nature Protocols 3 , - 1 - 7 (2008)
- Nicholas E Leadbeater , Jason R Schmink, Use of Raman spectroscopy as a tool for in situ monitoring of microwave-promoted reactions. Dalton Trans. 2008 Mar 14; (10):1341-5
- Nicholas E Leadbeater , Rebecca J Smith, In situ Raman spectroscopy as a probe for the effect of power on microwave-promoted Suzuki coupling reactions Org Biomol Chem. 2007 Sep 7;5 (17):2770-4
- Nicholas E Leadbeater , Rebecca J Smith , T Michael Barnard . Using in situ Raman monitoring as a tool for rapid optimisation and scale-up of microwave-promoted organic synthesis: esterification as an example. Org Biomol Chem. 2007 Mar 7;5 (5):822-5
- Nicholas E Leadbeater , Rebecca J Smith, Real-time monitoring of microwave-promoted suzuki coupling reactions using in situ Raman spectroscopy. Org Lett. 8(20):4589-91.Org Lett. 2006 Sep 28;8 (20):4589-91
- Barnard, T. M. and N. E. Leadbeater. 2006. Real-time monitoring of microwave-promoted organometallic ligand-substitution reactions using in situ Raman spectroscopy. Chem Commun (Camb). 2006 Sep 14; 34:3615-6.